Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | CASP6 | P55212 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | PRKACA | P17612 | 1/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28099167 | 0.84 | ALDH1A1 (0.56) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL7051300 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL5707211 | 0.81 | CRHBP (0.57) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL27739230 | 0.81 | HNF4A (0.54) | ALDH1A1TDP1CRHBPCRHR2S100A4 | |
| SCHEMBL10774151 | 0.81 | TDP1 (0.53) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL29069346 | 0.79 | TDP1 (0.55) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL16937118 | 0.79 | TDP1 (0.55) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL28661972 | 0.79 | GPR35 (0.53) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL30139580 | 0.79 | TDP1 (0.55) | ALDH1A1TDP1CRHBPCRHR2CASP6 | |
| SCHEMBL3758845 | 0.79 | ALDH1A1 (0.55) | ALDH1A1TDP1CRHBPCRHR2CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274673-B1 | METHOD FOR PRODUCING 4-HYDROXY-3-NITROBIPHENYL | SALTIGO GMBH (DE) | 2006-10-11 | — | — | EP | disclosed |
| US-6610893-B2 | Selectively nitrating 4-hydroxybiphenyl in the position adjacent to the phenolic hydroxyl group | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-26 | — | — | US | disclosed |
| US-20030055294-A1 | Method for producing 4-hydroxy-3-nitrobiphenyl | LANXESS DEUTSCHLAND GMBH (DE) | 2003-03-20 | — | — | US | disclosed |
| EP-1274673-A1 | METHOD FOR PRODUCING 4-HYDROXY-3-NITROBIPHENYL | Bayer Aktiengesellschaft (DE) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001077061-A1 | METHOD FOR PRODUCING 4-HYDROXY-3-NITROBIPHENYL | BAYER AKTIENGESELLSCHAFT (DE) | 2001-10-18 | — | — | WO | disclosed |