Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.44 |
| ▸ | KDM6A | O15550 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230735 | 0.88 | ALDH1A1 (0.51) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL250150 | 0.82 | TOP2A (0.46) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL19717967 | 0.82 | TOP2A (0.46) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL250148 | 0.78 | TOP2A (0.53) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL22687002 | 0.78 | TOP2A (0.53) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL5335888 | 0.78 | TOP2A (0.53) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL9292548 | 0.77 | TOP2A (0.68) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL27925323 | 0.77 | TOP2A (0.52) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL171055 | 0.77 | TOP2A (0.62) | TOP2APTGS2ALDH1A1NPC1HPGD | |
| SCHEMBL29504749 | 0.77 | TOP2A (0.62) | TOP2APTGS2ALDH1A1NPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| US-20180320098-A1 | PROCESS FOR ENHANCING GASOLINE OCTANE BOOSTERS, GASOLINE BOOSTERS, AND GASOLINES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2018-11-08 | — | — | US | disclosed |
| EP-3383977-A1 | PROCESS FOR ENHANCING GASOLINE OCTANE BOOSTERS, GASOLINE BOOSTERS, AND GASOLINES | SABIC Global Technologies B.V. (NL) | 2018-10-10 | — | — | EP | disclosed |
| WO-2017093913-A1 | PROCESS FOR ENHANCING GASOLINE OCTANE BOOSTERS, GASOLINE BOOSTERS, AND GASOLINES | SABIC GLOBAL TECHNOLOGIES B.V. (NL) | 2017-06-08 | — | — | WO | disclosed |
| EP-1325067-B1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEM CO (US) | 2006-09-06 | — | — | EP | disclosed |
| EP-1325067-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2003-07-09 | — | — | EP | disclosed |
| US-6492032-B1 | MIXTURE OF BENZOXAZOLYL STILBENES WITH A BIS(BENZOXAZOLYL)-NAPHTHALENE, BIS(BENZOXAZOLYL)THIOPHENE, A PYRAZOLINE AND/OR A COURMARIN; PHOTOGRAPHIC FILMS | EASTMAN CHEMICAL COMPANY | 2002-12-10 | — | — | US | disclosed |
| WO-2002031035-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2002-04-18 | — | — | WO | disclosed |
| US-5152922-A | 1,4-DISTYRYLBENZENE COMPOUNDS AND MIXTURES THEREOF WITH OTHER 1,4-DISTYRYBENZENE COMPOUNDS | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| US-4416795-A | Mixtures of optical brighteners | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-22 | — | — | US | disclosed |