SCHEMBL22687002

SCHEMBL22687002

C(=C\c1ccccc1-c1nc2ccccc2o1)\c1ccccc1-c1nc2ccccc2o1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TOP2A P11388 1/20 0.53
ALDH1A1 P00352 7/20 0.51
NPC1 O15118 7/20 0.51
RAB9A P51151 6/20 0.51
HPGD P15428 6/20 0.51
KDM4E B2RXH2 6/20 0.51
HSD17B10 Q99714 5/20 0.51
MAPT P10636 5/20 0.51
TP53 P04637 5/20 0.51
SMN1; SMN2 Q16637 4/20 0.51
PKM P14618 2/20 0.51
GLA P06280 1/20 0.51
GAA P10253 1/20 0.51
CASP1 P29466 1/20 0.51
CASP7 P55210 1/20 0.51
KDM6B O15054 1/20 0.51
KDM6A O15550 1/20 0.51
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
HCRTR1 O43613 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5335888 1.00 TOP2A (0.53) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL250148 1.00 TOP2A (0.53) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL285170 0.92 ALDH1A1 (0.48) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL285168 0.92 ALDH1A1 (0.48) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL8593114 0.92 SNCA (0.48) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL28887970 0.92 ALDH1A1 (0.48) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL7567677 0.92 PTGS2 (0.50) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL6688214 0.87 MEN1 (0.49) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL6810407 0.86 TOP2A (0.50) TOP2AALDH1A1NPC1RAB9AHPGD
SCHEMBL2477874 0.86 NPC1 (0.53) TOP2AALDH1A1NPC1RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11680116-B2 Polymeric antimicrobial surfactant Poly Group LLC (US) 2023-06-20 US disclosed
US-20200369800-A1 POLYMERIC ANTIMICROBIAL SURFACTANT Poly Group LLC 2020-11-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680116-B2 Polymeric antimicrobial surfactant PUF60, DLST, CAPG TOP2A 2637/4885ALDH1A1 3706/4885NPC1 1151/4885
US-20200369800-A1 POLYMERIC ANTIMICROBIAL SURFACTANT PUF60, DLST, CAPG TOP2A 2637/4885ALDH1A1 3706/4885NPC1 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.