Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.58 |
| ▸ | CNR1 | P21554 | 2/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.52 |
| ▸ | STAT5B | P51692 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7702197 | 0.82 | RIPK1 (0.43) | TAS2R14 | |
| SCHEMBL7705112 | 0.80 | STAT5B (0.46) | TAS2R14CNR2STAT5BPTPN1STAT3 | |
| SCHEMBL12550326 | 0.78 | STAT5B (0.52) | TAS2R14CNR2STAT5B | |
| SCHEMBL17661786 | 0.77 | TAS2R14 (0.40) | TAS2R14CNR1CNR2STAT5BLMNA | |
| SCHEMBL12550044 | 0.77 | STAT5B (0.49) | TAS2R14STAT5BPTPN1 | |
| SCHEMBL7067656 | 0.76 | STAT5B (0.44) | TAS2R14CNR2STAT5BPTPN1STAT3 | |
| SCHEMBL5708145 | 0.76 | C5AR1 (0.49) | TAS2R14CNR1CNR2STAT5BSTAT3 | |
| SCHEMBL9181881 | 0.75 | STAT5B (0.45) | TAS2R14CNR2STAT5BPTPN1STAT3 | |
| SCHEMBL8879054 | 0.75 | STAT5B (0.45) | TAS2R14STAT5BLMNAPTPN1STAT3 | |
| SCHEMBL9986889 | 0.74 | KMT2A (0.46) | TAS2R14LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1419126-B1 | FLUOROUS NUCLEOPHILIC SUBSTITUTION OF ALCOHOLS AND REAGENTS FOR USE THEREIN | UNIV PITTSBURGH (US) | 2006-11-02 | — | — | EP | disclosed |
| US-6806357-B1 | REACTING THE ALCOHOL AND A NUCLEOPHILE WITH AN AZODICARBOXYLATE AND A PHOSPHINE. AT LEAST ONE OF THE AZODICARBOXYLATE AND THE PHOSPHINE INCLUDES AT LEAST ONE FLUOROUS TAG | UNIVERSITY OF PITTSBURGH | 2004-10-19 | — | — | US | disclosed |