SCHEMBL5708283

SCHEMBL5708283

O=C(NC(C(=O)O)C(=O)O)c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC1A2 P43004 1/20 0.58
HDAC3 O15379 1/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
IDO1 P14902 1/20 0.54
ALOX15 P16050 1/20 0.54
HDAC1 Q13547 1/20 0.54
CA9 Q16790 1/20 0.54
HDAC7 Q8WUI4 1/20 0.54
HDAC2 Q92769 1/20 0.54
HSD17B10 Q99714 1/20 0.54
HDAC8 Q9BY41 1/20 0.54
HDAC6 Q9UBN7 1/20 0.54
NCOR2 Q9Y618 1/20 0.54
LMNA P02545 2/20 0.53
HPGD P15428 2/20 0.53
CTRB1 P17538 6/20 0.52
GAA P10253 1/20 0.50
ALDH1A1 P00352 2/20 0.49
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14714512 0.88 HPGDS (0.66) LMNAGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL28458590 0.88 SLC1A2 (0.51) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL14128517 0.88 SLC1A2 (0.56) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL11393389 0.86 ALDH1A1 (0.52) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL7208912 0.82 LMNA (0.50) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL5908060 0.82 SLC1A2 (0.75) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL28898272 0.82 SLC1A2 (0.46) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL28641833 0.81 HDAC3 (0.58) SLC1A2HDAC3CA12CA1IDO1
SCHEMBL25159032 0.81 NPC1 (0.53) SLC1A2CA1LMNASMN1; SMN2RAB9A
SCHEMBL14715137 0.81 TPMT (0.50) CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0310555-B1 DERIVATIVES OF 1,5-DIPHENYL-1,2,4-TRIAZOLE-3-CARBOXYLIC ACID FOR CROP PROTECTION AGAINST THE PHYTOTOXIC ACTIVITY OF HERBICIDES CIBA-GEIGY AG (CH) 1993-02-10 EP claimed
JP-57106652-A None JP disclosed
CN-118265703-A Therapeutic co-crystals of 3- { [5- (azetidin-1-ylcarbonyl) pyrazin-2-yl ] oxy } -5- { [ (1S) -1-methyl-2- (methoxy) ethyl ] oxy) -N- (5-methylpyrazin-2-yl) benzamide 康杜英国管理有限公司 2024-06-28 CN disclosed
WO-2019181789-A1 SEALING ADHESIVE 味の素株式会社 2019-09-26 WO disclosed
CN-100513386-C Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils DOMP S P A (IT) 2009-07-15 CN disclosed
EP-1711504-A2 DERIVATIVES OF CEPHALOSPORIN AND CLAVULANIC ACID FOR DETECTING BETA-LACTAMASE IN A SAMPLE Molecular Probes Inc. (US) 2006-10-18 EP disclosed
WO-2005071096-A9 DERIVATIVES OF CEPHALOSPORIN AND CLAVULANIC ACID FOR DETECTING BETA-LACAMASE IN A SAMPLE 2006-02-02 WO disclosed
WO-2005071096-A2 DERIVATIVES OF CEPHALOSPORIN AND CLAVULANIC ACID FOR DETECTING BETA-LACAMASE IN A SAMPLE MOLECULAR PROBES, INC. (US) 2005-08-04 WO disclosed
CN-1479715-A Amides for inhibiting interleukin 8-induced chemotaxis of neutrophils ��ķ�ɷ����޹�˾ 2004-03-03 CN disclosed
WO-2001014335-A1 PROCESS FOR PREPARATION OF PAROXETIN INTERMEDIATE SMITHKLINE BEECHAM P.L.C. (GB) 2001-03-01 WO disclosed
US-5217524-A 1,5-diphenyl-1,2,4-triazole-3-carboxylic acid derivatives for the protection of cultivated plants from the phytotoxic action of herbicides CIBA-GEIGY CORPORATION (US) 1993-06-08 US disclosed
US-5077413-A Preferential herbicides CIBA-GEIGY CORPORATION (US) 1991-12-31 US disclosed
JP-S57106652-A NOVEL GLUTAMIC ACID DERIVATIVE AND PREPARATION OF GLUTAMIC ACID TYPE DERIVATIVE NIPPON IYAKUHIN KOGYO KK 1982-07-02 JP disclosed