Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 8/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | MTOR | P42345 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13150316 | 0.79 | SIGMAR1 (0.67) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL6550825 | 0.79 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL2962629 | 0.79 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL3589625 | 0.78 | ALDH1A1 (0.51) | SMN1; SMN2CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL11399131 | 0.78 | SIGMAR1 (0.81) | SIGMAR1 | |
| SCHEMBL7329630 | 0.78 | SIGMAR1 (0.81) | SIGMAR1TSHR | |
| SCHEMBL7398421 | 0.75 | SIGMAR1 (0.65) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL16226519 | 0.75 | HDAC4 (0.69) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 | |
| SCHEMBL8550741 | 0.74 | POLB (0.55) | SMN1; SMN2TP53MAPTMAPK1RAB9A | |
| SCHEMBL10042374 | 0.74 | SIGMAR1 (0.73) | SIGMAR1SMN1; SMN2TP53CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1714639-A1 | Cosmetic compositions containing piperazine derivatives | L'OREAL (FR) | 2006-10-25 | — | — | EP | disclosed |