Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 2/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 3/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 2/20 | 0.35 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL553509 | 0.84 | GPR119 (0.49) | MEN1KMT2A | |
| SCHEMBL553508 | 0.84 | GPR119 (0.49) | MEN1KMT2A | |
| SCHEMBL554690 | 0.84 | GPR119 (0.49) | MEN1KMT2A | |
| SCHEMBL570573 | 0.83 | MGLL (0.43) | MGLLMEN1KMT2ABCL2BCL2L1 | |
| SCHEMBL554243 | 0.83 | BCL2 (0.47) | MGLLBCL2BCL2L1CNR1CNR2 | |
| SCHEMBL554868 | 0.83 | BCL2 (0.47) | MGLLBCL2BCL2L1CNR1CNR2 | |
| SCHEMBL554242 | 0.83 | BCL2 (0.47) | MGLLBCL2BCL2L1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL555336 | 0.82 | BCL2 (0.47) | MGLLBCL2BCL2L1CNR1CNR2 | |
| Hydrochloric Acid SCHEMBL555006 | 0.82 | BCL2 (0.47) | MGLLBCL2BCL2L1CNR1CNR2 | |
| SCHEMBL15536288 | 0.80 | FPR2 (0.49) | MGLLMEN1KMT2AFPR2PROKR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601177-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | AstraZeneca AB (SE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017251-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |