Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 5/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 5/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.32 |
| ▸ | PPARD | Q03181 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27668431 | 0.87 | LTB4R (0.32) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL27556880 | 0.83 | ALDH1A1 (0.37) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL3838340 | 0.80 | LTB4R (0.36) | LTB4RLTB4R2PPARGPPARDPPARA | |
| SCHEMBL6184688 | 0.72 | — | — | |
| SCHEMBL3838058 | 0.72 | ALDH1A1 (0.34) | PPARDBCHE | |
| SCHEMBL27553731 | 0.65 | ACACB (0.34) | — | |
| SCHEMBL13672475 | 0.65 | ADRB1 (0.38) | — | |
| SCHEMBL27530769 | 0.65 | ADRB2 (0.47) | — | |
| SCHEMBL27533607 | 0.64 | ACACB (0.34) | — | |
| SCHEMBL27553728 | 0.63 | ACACB (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1715860-A1 | COMBINATION OF BENZOTHIAZOL-2-ONE BETA2 ADRENOCEPTOR AGONISTS AND CORTICOSTEROIDS FOR THE TREATMENT OF RESPIRATORY DISEASES | Novartis AG (CH) | 2006-11-02 | — | — | EP | disclosed |
| WO-2005074924-A1 | COMBINATION OF BENZOTHIAZOL-2-ONE BETA2 ADRENOCEPTOR AGONISTS AND CORTICOSTEROIDS FOR THE TREATMENT OF RESPIRATORY DISEASES | NOVARTIS AG (CH) | 2005-08-18 | — | — | WO | disclosed |
| EP-1529038-A1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | Novartis AG (CH) | 2005-05-11 | — | — | EP | disclosed |
| WO-2004016601-A1 | BENZOTHIAZOLE DERIVATIVES HAVING BETA-2-ADRENORECEPTOR AGONIST ACTIVITY | NOVARTIS AG (CH) | 2004-02-26 | — | — | WO | disclosed |