Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.58 |
| ▸ | CCR3 | P51677 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.52 |
| ▸ | MC5R | P33032 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936632 | 0.85 | MCHR1 (0.69) | ACHEMCHR1CCR3SIGMAR1KMT2A | |
| SCHEMBL5709427 | 0.84 | OPRM1 (0.64) | OPRM1SIGMAR1CHRM2CHRM3 | |
| SCHEMBL4125301 | 0.82 | ACHE (0.57) | ACHEMCHR1CCR3SIGMAR1POLB | |
| SCHEMBL5709435 | 0.80 | ACHE (0.60) | ACHEOPRM1SIGMAR1KMT2ACHRM2 | |
| SCHEMBL5709507 | 0.79 | OPRM1 (0.52) | CCR3OPRM1CHRM2CHRM3 | |
| SCHEMBL5709518 | 0.79 | OPRM1 (0.52) | OPRM1SIGMAR1POLBKMT2ACHRM2 | |
| SCHEMBL7304448 | 0.78 | MCHR1 (0.65) | ACHEMCHR1CCR3SIGMAR1KMT2A | |
| SCHEMBL5709432 | 0.78 | OPRM1 (0.55) | OPRM1SIGMAR1CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL1814858 | 0.78 | OPRM1 (0.62) | OPRM1SIGMAR1KMT2ACHRM2CHRM3 | |
| SCHEMBL8269816 | 0.76 | MCHR1 (0.62) | ACHEMCHR1SIGMAR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |