SCHEMBL3936632

SCHEMBL3936632

CN(C(=O)O)C1CCN(Cc2ccc3ccccc3c2)CC1

nearest known ligand 0.69

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MCHR1 Q99705 4/20 0.69
CCR3 P51677 1/20 0.69
ACHE P22303 1/20 0.61
SIGMAR1 Q99720 3/20 0.59
CCR4 P51679 1/20 0.57
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.54
DRD2 P14416 1/20 0.53
HTR2A P28223 1/20 0.53
HTR2C P28335 1/20 0.53
HTR2B P41595 1/20 0.53
KCNH2 Q12809 1/20 0.53
FAAH O00519 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3938953 0.88 CCR4 (0.58) MCHR1CCR3SIGMAR1CCR4DRD2
SCHEMBL5709408 0.85 ACHE (0.59) MCHR1CCR3ACHESIGMAR1KMT2A
SCHEMBL784863 0.85 SIGMAR1 (0.68) ACHESIGMAR1DRD2HTR2AHTR2C
SCHEMBL9593681 0.84 CCR3 (0.65) MCHR1CCR3ACHESIGMAR1
SCHEMBL4125301 0.84 ACHE (0.57) MCHR1CCR3ACHESIGMAR1KMT2A
SCHEMBL3942391 0.83 CHRM4 (0.62) CCR3SIGMAR1DRD2HTR2AHTR2C
SCHEMBL7304448 0.80 MCHR1 (0.65) MCHR1CCR3ACHESIGMAR1KMT2A
SCHEMBL3593317 0.80 SIGMAR1 (0.55) SIGMAR1KMT2AMEN1DRD2HTR2A
SCHEMBL3605410 0.80 ALDH1A1 (0.53) CCR3ACHESIGMAR1KMT2AMEN1
Hydrochloric Acid SCHEMBL3592267 0.79 SIGMAR1 (0.54) SIGMAR1DRD2HTR2AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1720550-B1 DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS SANOFI AVENTIS (FR) 2009-04-15 EP claimed
EP-1720550-B1 DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS SANOFI AVENTIS (FR) 2009-04-15 EP disclosed