Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | UBE2M | P61081 | 3/20 | 0.52 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709432 | 0.83 | OPRM1 (0.55) | OPRM1KDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL27674795 | 0.83 | ALDH1A1 (0.45) | OPRM1UBE2MDCUN1D1TP53KDM4E | |
| SCHEMBL5709427 | 0.80 | OPRM1 (0.64) | OPRM1KDM4EALDH1A1CHRM2CHRM3 | |
| SCHEMBL5709452 | 0.80 | OPRM1 (0.46) | OPRM1UBE2MDCUN1D1KDM4EALDH1A1 | |
| SCHEMBL5709465 | 0.79 | OPRM1 (0.48) | OPRM1UBE2MDCUN1D1KDM4EALDH1A1 | |
| SCHEMBL5709506 | 0.79 | SIGMAR1 (0.50) | OPRM1 | |
| SCHEMBL5709408 | 0.79 | ACHE (0.59) | OPRM1CHRM2CHRM3CCR3 | |
| SCHEMBL5709490 | 0.79 | OPRM1 (0.51) | OPRM1UBE2MDCUN1D1KDM4EALDH1A1 | |
| SCHEMBL1907763 | 0.77 | KCNH2 (0.57) | OPRM1UBE2MDCUN1D1KDM4EALDH1A1 | |
| SCHEMBL5709513 | 0.77 | OPRM1 (0.49) | OPRM1UBE2MDCUN1D1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |