Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5709474 | 0.78 | AR (0.40) | KDM1AGSK3BBACE1KCNA5RAB9A | |
| SCHEMBL5709462 | 0.75 | KDM1A (0.45) | KDM1ARAB9ASMN1; SMN2MRGPRX4FFAR1 | |
| SCHEMBL5709377 | 0.74 | FFAR1 (0.44) | KDM1AMRGPRX4FFAR1MAOBRXRA | |
| SCHEMBL5709343 | 0.72 | KDM1A (0.46) | KDM1ARAB9ASMN1; SMN2MRGPRX4MAOB | |
| SCHEMBL5709523 | 0.69 | KCNA5 (0.45) | KCNA5RAB9ASMN1; SMN2ARMAPT | |
| SCHEMBL5709371 | 0.69 | KDM1A (0.47) | KDM1AMAOBAR | |
| SCHEMBL27660688 | 0.69 | KDM1A (0.47) | KDM1ASMN1; SMN2MAOBLMNAAR | |
| SCHEMBL5709411 | 0.69 | LTA4H (0.38) | KDM1ARAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL5709412 | 0.69 | KDM1A (0.38) | KDM1AMAOBRXRARXRBRXRG | |
| SCHEMBL27660872 | 0.68 | KDM1A (0.37) | KDM1AFFAR1MAOBAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727785-A1 | PHENYL INDAN DERIVATIVES | H.Lundbeck A/S (DK) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005087708-A1 | PHENYL INDAN DERIVATIVES | H. LUNDBECK A/S (DK) | 2005-09-22 | — | — | WO | disclosed |