SCHEMBL744815

SCHEMBL744815

Nc1ccccc1C1CC1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 2/20 0.45
CYP3A4 P08684 1/20 0.45
CASP1 P29466 1/20 0.45
CASP7 P55210 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HTR2C P28335 5/20 0.39
ALDH1A1 P00352 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
IDO1 P14902 4/20 0.39
GAA P10253 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 1/20 0.36
USP2 O75604 1/20 0.36
KMT2A Q03164 1/20 0.36
GID4 Q8IVV7 1/20 0.36
TSHR P16473 2/20 0.36
HTR2A P28223 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL22169152 0.91 TSHR (0.48) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL1068978 0.90 NOS1 (0.41) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL1067058 0.90 KDM4E (0.44) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL8932238 0.89 MEN1 (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL8786474 0.88 KDM4E (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL570948 0.88 KDM4E (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL4849477 0.88 KDM4E (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL9377442 0.88 KDM4E (0.47) ALOX15CYP3A4CASP1CASP7SMN1; SMN2
SCHEMBL3553262 0.84 HTR2C (0.60) HTR2C
SCHEMBL29922358 0.84 HTR2C (0.60) HTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 199 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117143007-A Tetrahydrocarbazole derivative and photocatalytic synthesis method thereof 陕西科技大学 2023-12-01 CN claimed
CN-114057623-A N-naphthyl indole derivative and synthetic method thereof 湖南第一师范学院 2022-02-18 CN claimed
CN-110669058-A Tricyclic quinolone carboxylic acid and preparation method thereof 江西农业大学 2020-01-10 CN claimed
EP-0577945-B1 Herbicide intermediate o-nitrophenyl cyclopropyl ketone and a method for the preparation thereof AMERICAN CYANAMID CO (US) 1996-08-14 EP claimed
EP-0030514-B1 ANILINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM FOR REGULATING PLANT-GROWTH RHONE-POULENC AGROCHIMIE (FR) 1983-08-17 EP claimed
EP-0030514-A1 Aniline derivatives, process for their preparation and compositions containing them for regulating plant-growth RHONE-POULENC AGROCHIMIE (FR) 1981-06-17 EP claimed
JP-11035531-A None JP disclosed
JP-62030772-A None JP disclosed
EP-4735114-A1 SUBSTITUTED THIENO [3,2-B]PYRIDINES AS INHIBITORS OF PROTEIN KINASES Masarykova Univerzita (CZ) 2026-05-06 EP disclosed
US-12503467-B2 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors IDEAYA BIOSCIENCES, INC. (US) 2025-12-23 US disclosed
US-20250381187-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME AMGEN INC. (US) 2025-12-18 US disclosed
US-12479845-B2 Imidazopyridine derivative compounds and use of same HANMI PHARM. CO., LTD. (KR) 2025-11-25 US disclosed
US-12440491-B2 KRAS G12C inhibitors and methods of using the same AMGEN INC. (US) 2025-10-14 US disclosed
EP-0711757-A1 3-(4-phenylpiperazin-1-yl)propyl-amino, thio and oxy -pyridine, pyrimidine and benzene derivatives as alpha1-adrenoceptor antagonists F. Hoffmann-La Roche AG (CH) 1996-05-15 EP disclosed
WO-1996007657-A1 PYRIMIDO[5,4-D]PYRIMIDINES, DRUGS CONTAINING THESE COMPOUNDS, THEIR USE, AND PROCESS FOR PREPARING THEM DR. KARL THOMAE GMBH (DE) 1996-03-14 WO disclosed
JP-S6230772-A CYCLOPROPYLANILINE DERIVATIVE TOKYO TANABE CO LTD 1987-02-09 JP disclosed
EP-0149237-A2 1,4-Dihydropyrazines, process for their preparation and their use in medicines BAYER AG (DE) 1985-07-24 EP disclosed
EP-0030514-B1 ANILINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM FOR REGULATING PLANT-GROWTH RHONE-POULENC AGROCHIMIE (FR) 1983-08-17 EP disclosed
EP-0030514-A1 Aniline derivatives, process for their preparation and compositions containing them for regulating plant-growth RHONE-POULENC AGROCHIMIE (FR) 1981-06-17 EP disclosed
EP-0030514-A1 Aniline derivatives, process for their preparation and compositions containing them for regulating plant-growth RHONE-POULENC AGROCHIMIE (FR) 1981-06-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250381187-A1 KRAS G12C INHIBITORS AND METHODS OF USING THE SAME KRAS, NRAS, HRAS ALOX15 3170/4885CYP3A4 4739/4885CASP1 3637/4885
US-12440491-B2 KRAS G12C inhibitors and methods of using the same KRAS, NRAS, HRAS ALOX15 3170/4885CYP3A4 4739/4885CASP1 3637/4885
US-12479845-B2 Imidazopyridine derivative compounds and use of same KDM1A, KDM1B, KDM2A ALOX15 1758/4885CYP3A4 843/4885CASP1 1492/4885
US-12503467-B2 2-oxoquinazoline derivatives as methionine adenosyltransferase 2A inhibitors MAT2B, MAT2A, MAT1A ALOX15 4067/4885CYP3A4 3573/4885CASP1 4328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.