Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.49 |
| ▸ | F12 | P00748 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SI | P14410 | 1/20 | 0.46 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL570975 | 0.80 | MAOB (0.39) | MAOBMAOAMAPTCA1CA2 | |
| SCHEMBL570973 | 0.80 | MAOB (0.39) | MAOBMAOAMAPTCA1CA2 | |
| SCHEMBL570890 | 0.71 | MAOB (0.39) | MAOBMAOAMAPTGAACA1 | |
| SCHEMBL570888 | 0.71 | MAOB (0.39) | MAOBMAOAMAPTGAACA1 | |
| SCHEMBL15058644 | 0.71 | MAOB (0.73) | MAOBMAOAKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL28459677 | 0.71 | MAOB (0.62) | MAOBMAOAMAPTMGAMGAA | |
| SCHEMBL28459676 | 0.71 | MAOB (0.62) | MAOBMAOAMAPTMGAMGAA | |
| SCHEMBL570957 | 0.69 | MAPT (0.46) | MAOBMAOAACHEMAPTKMT2A | |
| SCHEMBL10080475 | 0.68 | MAOA (0.60) | MAOBMAOAGAACA12CA1 | |
| SCHEMBL571130 | 0.67 | GPR35 (0.41) | MAOBMAOAMAPTCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601183-A1 | COUMARIN-CHALCONES AS ANTICANCER AGENTS | Council Of Scientific & Industrial Research (IN) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017454-A1 | COUMARIN-CHALCONES AS ANTICANCER AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-02-09 | — | — | WO | disclosed |