SCHEMBL5709863

SCHEMBL5709863

COc1ccc(C(=O)c2ccc(O)cc2O)c(OC)c1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.75
RAB9A P51151 4/20 0.75
CYP3A4 P08684 6/20 0.65
HPGD P15428 5/20 0.65
LMNA P02545 4/20 0.65
CYP1A2 P05177 3/20 0.65
CYP2C19 P33261 3/20 0.65
PGR P06401 2/20 0.65
SLC6A2 P23975 2/20 0.65
ALOX15 P16050 2/20 0.65
ADORA3 P0DMS8 1/20 0.65
AR P10275 1/20 0.65
CHRM1 P11229 1/20 0.65
TBXA2R P21731 1/20 0.65
ADRA1A P35348 1/20 0.65
HIF1A Q16665 1/20 0.65
ALDH1A1 P00352 4/20 0.59
MAPK1 P28482 4/20 0.59
CYP2D6 P10635 1/20 0.59
PDE4A P27815 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29389720 1.00 NPC1 (0.75) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL6663420 0.95 NPC1 (0.83) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL30900821 0.92 NPC1 (0.89) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL93206 0.92 NPC1 (0.89) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL29419872 0.92 NPC1 (0.89) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL1348833 0.92 NPC1 (0.89) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL5709889 0.89 RAB9A (0.73) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL30375318 0.89 RAB9A (0.73) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL285924 0.87 NPC1 (0.79) NPC1RAB9ACYP3A4HPGDLMNA
SCHEMBL31575666 0.87 NPC1 (0.79) NPC1RAB9ACYP3A4HPGDLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025055600-A1 SURFACE TREATMENT METHOD FOR METAL OR ALLOY, AND METAL OR ALLOY PRODUCT 福耀玻璃工业集团股份有限公司 2025-03-20 WO claimed
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT THE PILOT INK CO., LTD. (JP) 2026-03-05 US disclosed
EP-3954745-B1 REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) 2026-01-07 EP disclosed
US-12460099-B2 Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment THE PILOT INK CO., LTD. (JP) 2025-11-04 US disclosed
US-12421411-B2 Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument KABUSHIKI KAISHA PILOT CORPORATION (JP) 2025-09-23 US disclosed
WO-2025055600-A1 SURFACE TREATMENT METHOD FOR METAL OR ALLOY, AND METAL OR ALLOY PRODUCT 福耀玻璃工业集团股份有限公司 2025-03-20 WO disclosed
US-20230383175-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2023-11-30 US disclosed
US-20230287259-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2023-09-14 US disclosed
EP-3404055-B1 COMPOSITION, FILM, GLASS ARTICLE, COMPOUND, HIGH PURITY COMPOSITION, METHOD FOR PRODUCING COMPOUND, AND METHOD FOR PRODUCING FILM FUJIFILM CORP (JP) 2023-08-16 EP disclosed
EP-4219186-A1 REVERSIBLE THERMOCHROMIC COMPOSITION AND REVERSIBLE THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING SAME The Pilot Ink Co., Ltd (JP) 2023-08-02 EP disclosed
EP-2899243-A1 LIQUID COMPOSITION AND GLASS ARTICLE Asahi Glass Company, Limited (JP) 2015-07-29 EP disclosed
US-20150183683-A1 LIQUID COMPOSITION AND GLASS ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2015-07-02 US disclosed
EP-2792486-A1 ANTIFOGGING ARTICLE, METHOD FOR PRODUCING SAME, COMPOSITION FOR FORMING WATER ABSORBENT LAYER, AND ARTICLE FOR TRANSPORTATION DEVICES Asahi Glass Company, Limited (JP) 2014-10-22 EP disclosed
US-20140295175-A1 ANTIFOGGING ARTICLE AND METHOD FOR MANUFACTURING THE SAME, WATER ABSORBING LAYER FORMING COMPOSITION, AND ARTICLE FOR TRANSPORTATION APPARATUS ASAHI GLASS COMPANY, LIMITED (JP) 2014-10-02 US disclosed
EP-2690145-A1 LIQUID COMPOSITION, METHOD FOR PRODUCING SAME, AND GLASS ARTICLE Asahi Glass Company, Limited (JP) 2014-01-29 EP disclosed
US-20140023860-A1 LIQUID COMPOSITION AND ITS PRODUCTION PROCESS, AND GLASS ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2014-01-23 US disclosed
US-20130071669-A1 COATING SOLUTION FOR FORMING ULTRAVIOLET-ABSORBING FILM AND ULTRAVIOLET-ABSORBING GLASS ARTICLE ASAHI GLASS COMPANY, LIMITED (JP) 2013-03-21 US disclosed
EP-1179435-B1 Reversible thermochromic composition having improved light-fastness and product comprising same PILOT INK CO LTD (JP) 2006-11-29 EP disclosed
US-6638620-B2 Discoloration sensitivity THE PILOT INK CO., LTD. (JP) 2003-10-28 US disclosed
EP-1179435-A1 Reversible thermochromic composition having improved light-fastness and product comprising same The Pilot Ink Co., Ltd. (JP) 2002-02-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062580-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT TYR, SCO2, HBB NPC1 1394/4885RAB9A 1027/4885CYP3A4 1450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.