Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 4/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATP4A | P20648 | 1/20 | 0.45 |
| ▸ | ATP4B | P51164 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255105 | 0.81 | LTB4R (0.55) | LTB4RCYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL29430028 | 0.81 | LTB4R (0.55) | LTB4RCYP19A1CYP2C9CYP2C19CYP1A2 | |
| SCHEMBL14801927 | 0.81 | CYP2D6 (0.57) | CYP2D6CYP3A4LTB4RXDHCYP19A1 | |
| SCHEMBL1263730 | 0.81 | PTGES (0.68) | PTGESAPPKDM4ENPC1ALDH1A1 | |
| SCHEMBL8618775 | 0.81 | MAPT (0.54) | LTB4RAPPKDM4EALDH1A1MAPT | |
| SCHEMBL5710084 | 0.80 | KDM4E (0.55) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8616869 | 0.80 | KDM4E (0.55) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL3741857 | 0.80 | LTB4R (0.48) | LTB4RAPPCYP19A1CYP2C9CYP2C19 | |
| SCHEMBL17536604 | 0.78 | LTB4R (0.57) | LTB4RKDM4E | |
| SCHEMBL227249 | 0.77 | LTB4R (0.59) | LTB4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1179435-B1 | Reversible thermochromic composition having improved light-fastness and product comprising same | PILOT INK CO LTD (JP) | 2006-11-29 | — | — | EP | disclosed |
| US-6638620-B2 | Discoloration sensitivity | THE PILOT INK CO., LTD. (JP) | 2003-10-28 | — | — | US | disclosed |
| EP-1179435-A1 | Reversible thermochromic composition having improved light-fastness and product comprising same | The Pilot Ink Co., Ltd. (JP) | 2002-02-13 | — | — | EP | disclosed |