Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11244350 | 0.67 | — | — | |
| SCHEMBL15478105 | 0.65 | ALDH1A1 (0.38) | GAALMNAKDM4EHPGDMAPT | |
| SCHEMBL6164008 | 0.64 | HPGD (0.62) | GAALMNAKDM4EHPGDMAPT | |
| SCHEMBL444616 | 0.64 | L3MBTL1 (0.46) | GAALMNAKDM4EHPGDMAPT | |
| Acetic Acid SCHEMBL31758441 | 0.63 | HPGD (0.45) | GAALMNAKDM4EHPGDMAPT | |
| SCHEMBL5710091 | 0.62 | ALDH1A1 (0.36) | LMNAHPGDMAPTKMT2AALDH1A1 | |
| SCHEMBL4273011 | 0.61 | CYP17A1 (0.39) | LMNAKDM4EMAPTKMT2AALDH1A1 | |
| SCHEMBL11607730 | 0.61 | ALDH1A1 (0.34) | GAALMNAKDM4EHPGDMAPT | |
| SCHEMBL9497401 | 0.60 | L3MBTL1 (0.39) | LMNAHPGDMAPTKMT2AALDH1A1 | |
| SCHEMBL1072621 | 0.60 | KDM4E (0.49) | GAALMNAKDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | claimed |
| EP-1311231-B1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | HENKEL KGAA (DE) | 2006-11-22 | — | — | EP | claimed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | claimed |
| EP-1311231-A1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-21 | — | — | EP | claimed |
| WO-2001097762-A1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | claimed |
| EP-1732896-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | Aventis Pharmaceuticals Inc. (US) | 2006-12-20 | — | — | EP | disclosed |
| EP-1311231-B1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | HENKEL KGAA (DE) | 2006-11-22 | — | — | EP | disclosed |
| WO-2005097750-A1 | SUBSTITUTED PYRIDONES AS INHIBITORS OF POLY(ADP-RIBOSE) POLYMERASE (PARP) | AVENTIS PHARMACEUTICALS INC. (US) | 2005-10-20 | — | — | WO | disclosed |
| EP-1311231-A1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-05-21 | — | — | EP | disclosed |
| WO-2001097762-A1 | AGENT FOR COLOURING KERATIN-CONTAINING FIBRES COMPRISING AT LEAST ONE OXOCYCLOPENTENE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-12-27 | — | — | WO | disclosed |