SCHEMBL5710317

SCHEMBL5710317

Nc1ccc(C(=O)Oc2ccc3ccccc3c2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.75
MAPT P10636 2/20 0.75
MEN1 O00255 1/20 0.75
TDP1 Q9NUW8 1/20 0.75
NR1H4 Q96RI1 1/20 0.55
ALDH1A1 P00352 2/20 0.54
HSD17B10 Q99714 1/20 0.54
CYP3A4 P08684 1/20 0.54
F2 P00734 3/20 0.53
PRSS1 P07477 3/20 0.53
PRSS2 P07478 2/20 0.53
PRSS3 P35030 2/20 0.53
PKM P14618 1/20 0.53
PARP10 Q53GL7 1/20 0.51
CA12 O43570 2/20 0.51
CA9 Q16790 2/20 0.51
MMP1 P03956 2/20 0.50
MMP12 P39900 1/20 0.50
HGFAC Q04756 2/20 0.49
TMPRSS2 O15393 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13292773 0.93 KMT2A (0.64) KMT2AMAPTMEN1TDP1NR1H4
SCHEMBL11649516 0.90 KMT2A (0.60) KMT2AMAPTMEN1TDP1NR1H4
SCHEMBL1639878 0.86 KMT2A (1.00) KMT2AMAPTMEN1TDP1ALDH1A1
SCHEMBL30523105 0.86 KMT2A (1.00) KMT2AMAPTMEN1TDP1ALDH1A1
SCHEMBL6052916 0.85 KMT2A (0.58) KMT2AMAPTMEN1TDP1NR1H4
SCHEMBL8851038 0.85 KMT2A (0.77) KMT2AMAPTMEN1TDP1ALDH1A1
Ammonia Solution, Strong SCHEMBL11705203 0.84 KMT2A (0.96) KMT2AMAPTMEN1TDP1ALDH1A1
SCHEMBL4132832 0.84 KMT2A (0.57) KMT2AMAPTMEN1TDP1NR1H4
SCHEMBL14029064 0.83 KMT2A (0.75) KMT2AMAPTMEN1TDP1ALDH1A1
SCHEMBL10627535 0.83 KMT2A (0.75) KMT2AMAPTMEN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1295866-B1 4-membered ring compound and optical phase retardation plate using the same FUJI PHOTO FILM CO LTD (JP) 2006-11-02 EP disclosed
US-6811833-B2 BIREFRINGEMENT FILM FUJI PHOTO FILM CO., LTD. (JP) 2004-11-02 US disclosed
US-20030102458-A1 4-Membered ring compound and optical phase optical retardation plate using the same FUJIFILM CORPORATION (JP) 2003-06-05 US disclosed
EP-1295866-A1 4-membered ring compound and optical phase retardation plate using the same FUJI PHOTO FILM CO., LTD. (JP) 2003-03-26 EP disclosed