Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 3/20 | 0.34 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711428 | 0.81 | ACE (0.38) | HSD11B1TSHRKMT2AMEN1PREP | |
| SCHEMBL7417378 | 0.78 | TSHR (0.48) | HSD11B1TSHRKMT2AALOX15MEN1 | |
| SCHEMBL7417381 | 0.78 | TSHR (0.48) | HSD11B1TSHRKMT2AALOX15MEN1 | |
| SCHEMBL29133796 | 0.78 | HSD11B1 (0.54) | HSD11B1KMT2AMEN1USP30SPR | |
| SCHEMBL24684941 | 0.76 | HSD11B1 (0.56) | HSD11B1KMT2AMEN1USP30SPR | |
| SCHEMBL7355350 | 0.75 | TSHR (0.44) | TSHRKMT2AALOX15MEN1PREP | |
| SCHEMBL26666679 | 0.75 | HSD11B1 (0.54) | HSD11B1USP30SPRKDM4D | |
| SCHEMBL3929534 | 0.75 | HSD11B1 (0.55) | HSD11B1USP30ALDH1A1 | |
| SCHEMBL12938720 | 0.74 | HSD11B1 (0.47) | HSD11B1TSHRKMT2AMEN1USP30 | |
| SCHEMBL13738053 | 0.72 | HSD11B1 (0.62) | HSD11B1KMT2AMEN1USP30SPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |
| EP-1103560-A1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2001-05-30 | — | — | EP | disclosed |