Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PREP | P48147 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | CKS1B | P61024 | 1/20 | 0.40 |
| ▸ | SKP1 | P63208 | 1/20 | 0.40 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7417378 | 0.97 | TSHR (0.48) | TSHRKMT2ACTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL7419142 | 0.89 | KMT2A (0.50) | TSHRKMT2ACTSKALDH1A1HSD11B1 | |
| SCHEMBL7417375 | 0.88 | CTSK (0.43) | TSHRKMT2ACTSKALDH1A1HSD11B1 | |
| SCHEMBL7355350 | 0.82 | TSHR (0.44) | TSHRKMT2ACTSKALDH1A1SMN1; SMN2 | |
| SCHEMBL21184011 | 0.80 | CTSK (0.48) | CTSKALDH1A1HSD11B1CYP2C9EPHX1 | |
| SCHEMBL15373447 | 0.78 | CTSK (0.54) | CTSKHSD11B1CYP2C9EPHX1NAMPT | |
| SCHEMBL5711219 | 0.78 | HSD11B1 (0.44) | TSHRKMT2AALDH1A1SMN1; SMN2HSD11B1 | |
| SCHEMBL6187601 | 0.78 | CTSK (0.56) | CTSKHSD11B1CYP2C9EPHX1NAMPT | |
| SCHEMBL15297472 | 0.77 | CTSK (0.52) | CTSKHSD11B1CYP2C9EPHX1NAMPT | |
| SCHEMBL20093573 | 0.77 | CTSK (0.52) | CTSKALDH1A1HSD11B1CYP2C9EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |