Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 3/20 | 0.45 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CTSL | P07711 | 2/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711193 | 0.88 | CMA1 (0.45) | DPP4ACEMMP8ADORA3ADORA2A | |
| SCHEMBL5711405 | 0.87 | DPP4 (0.51) | DPP4ACEPREPSYKCTSL | |
| SCHEMBL7664388 | 0.86 | ADORA3 (0.45) | DPP4KLK7KLK5PREPMMP8 | |
| SCHEMBL5711341 | 0.86 | DPP4 (0.55) | DPP4ACEPREPCTSLCTSK | |
| SCHEMBL5711449 | 0.85 | DPP4 (0.56) | DPP4ACEPREPCTSLCTSK | |
| SCHEMBL5711384 | 0.84 | CTSK (0.55) | DPP4CTSLCTSKCTSBCTSS | |
| SCHEMBL5711367 | 0.83 | ACE (0.48) | DPP4ACEPREPCASP1 | |
| SCHEMBL5711352 | 0.81 | PREP (0.57) | DPP4ACEPREPCTSLCTSK | |
| SCHEMBL7668118 | 0.81 | KLK7 (0.43) | KLK7KLK5ACESYKMMP8 | |
| SCHEMBL5711350 | 0.81 | DPP4 (0.53) | DPP4ACECTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |