Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.57 |
| ▸ | ACE | P12821 | 3/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CTSK | P43235 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711229 | 0.89 | CAPN1 (0.58) | PREPACEDPP4CAPN1CTSK | |
| SCHEMBL5711384 | 0.88 | CTSK (0.55) | DPP4CTSKCTSLCTSBCTSS | |
| SCHEMBL5711341 | 0.87 | DPP4 (0.55) | PREPACEDPP4CTSKCTSL | |
| SCHEMBL7667089 | 0.87 | CTSL (0.53) | PREPACEDPP4CAPN1CYP3A4 | |
| SCHEMBL7667094 | 0.87 | CTSL (0.53) | PREPACEDPP4CAPN1CYP3A4 | |
| SCHEMBL5711367 | 0.86 | ACE (0.48) | PREPACEDPP4CAPN1CYP1A2 | |
| SCHEMBL5711449 | 0.86 | DPP4 (0.56) | PREPACEDPP4CTSKCTSL | |
| SCHEMBL5711325 | 0.86 | DPP4 (0.49) | PREPACEDPP4CYP1A2CYP3A4 | |
| SCHEMBL5711354 | 0.85 | PREP (0.51) | PREPACEDPP4CAPN1CYP3A4 | |
| SCHEMBL7668101 | 0.84 | PREP (0.48) | PREPACEDPP4CAPN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |