Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | PREP | P48147 | 4/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | CASP2 | P42575 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP5 | P51878 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | CASP9 | P55211 | 1/20 | 0.46 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.46 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.43 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711229 | 0.87 | CAPN1 (0.58) | ACEDPP4PREPCASP1CASP3 | |
| SCHEMBL5711352 | 0.86 | PREP (0.57) | ACEDPP4PREPCAPN1CYP1A2 | |
| SCHEMBL5711430 | 0.86 | CASP1 (0.47) | ACEDPP4PREPCASP1CASP3 | |
| SCHEMBL7669769 | 0.85 | CASP1 (0.43) | DPP4PREPCASP1CASP3CASP2 | |
| SCHEMBL5711341 | 0.84 | DPP4 (0.55) | ACEDPP4PREP | |
| SCHEMBL5711405 | 0.84 | DPP4 (0.51) | ACEDPP4PREP | |
| SCHEMBL5711325 | 0.83 | DPP4 (0.49) | ACEDPP4PREPALDH1A1CYP1A2 | |
| SCHEMBL5711449 | 0.83 | DPP4 (0.56) | ACEDPP4PREPALDH1A1 | |
| SCHEMBL5711384 | 0.83 | CTSK (0.55) | DPP4 | |
| SCHEMBL5711342 | 0.83 | DPP4 (0.50) | ACEDPP4PREPCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103560-B1 | NOVEL THIAZOLIDINE DERIVATIVES | SANTEN PHARMACEUTICAL CO LTD (JP) | 2006-12-27 | — | — | EP | disclosed |
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |