Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 5/20 | 0.43 |
| ▸ | CES1 | P23141 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27635895 | 0.90 | PRSS1 (0.44) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL5711592 | 0.87 | MMP2 (0.47) | SLC6A2SLC6A3CES2CES1PRSS1 | |
| SCHEMBL3728429 | 0.82 | SLC6A2 (0.54) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL5702382 | 0.78 | SLC6A2 (0.54) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL633402 | 0.77 | SLC6A2 (0.50) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL5706428 | 0.77 | MEN1 (0.37) | SLC6A2SLC6A3CES2CES1LMNA | |
| SCHEMBL6582699 | 0.77 | SLC6A2 (0.47) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL207880 | 0.76 | CES2 (0.46) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL9889372 | 0.76 | MAPT (0.58) | SLC6A2SLC6A3PGRADRA2AADRA2B | |
| SCHEMBL434807 | 0.76 | MDM2 (0.57) | SLC6A2SLC6A3PGRADRA2AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1566175-B1 | Topical preparation comprising at least one aryloxime and bisabolol | MERCK PATENT GMBH (DE) | 2006-10-25 | — | — | EP | claimed |
| EP-0149242-B1 | 1-(2-HYDROXYARYL)-ALCAN-1-ONE OXIME, PREPARATION AND PHARMACEUTICAL USE | CHEMISCHE UND PHARMAZEUTISCHE FABRIKEN FAHLBERG-LIST GmbH (DE) | 1990-10-31 | — | — | EP | disclosed |
| EP-0149242-A2 | 1-(2-Hydroxyaryl)-alcan-1-one oxime, preparation and pharmaceutical use | CHEMISCHE UND PHARMAZEUTISCHE FABRIKEN FAHLBERG-LIST GmbH (DE) | 1985-07-24 | — | — | EP | disclosed |