Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALPG | P10696 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4007449 | 0.90 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1HTTS1PR2S1PR1 | |
| SCHEMBL14195847 | 0.85 | S1PR2 (0.53) | ALDH1A1L3MBTL1HTTS1PR2S1PR1 | |
| SCHEMBL13221149 | 0.83 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1HTTS1PR2S1PR1 | |
| SCHEMBL4005149 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1HTTS1PR2S1PR1 | |
| SCHEMBL7462928 | 0.80 | FDPS (0.51) | ALDH1A1HTTKMT2AMAPTMEN1 | |
| SCHEMBL14195840 | 0.80 | ALDH1A1 (0.45) | ALDH1A1HPGDTDP1MAPK1ALOX5 | |
| SCHEMBL15771884 | 0.79 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1HTTKMT2AMAPT | |
| SCHEMBL5712326 | 0.79 | S1PR2 (0.46) | ALDH1A1L3MBTL1HTTS1PR2S1PR1 | |
| SCHEMBL18033266 | 0.77 | FDPS (0.45) | ALDH1A1HTTKMT2AMAPTMEN1 | |
| SCHEMBL2650454 | 0.77 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1HTTKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383736-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-04-19 | — | — | EP | disclosed |
| EP-1383736-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2003002522-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-09 | — | — | WO | disclosed |