Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712342 | 0.83 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL14195844 | 0.83 | S1PR2 (0.50) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL21705960 | 0.83 | APP (0.46) | ALDH1A1ESR1THRATHRBAPP | |
| SCHEMBL4007449 | 0.81 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL565487 | 0.80 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL16610333 | 0.78 | APP (0.36) | ALDH1A1MAPTHPGDESR1THRA | |
| SCHEMBL2808932 | 0.77 | TPMT (0.54) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL4005253 | 0.76 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL14195847 | 0.75 | S1PR2 (0.53) | ALDH1A1L3MBTL1KMT2AMAPTHPGD | |
| SCHEMBL14195840 | 0.75 | ALDH1A1 (0.45) | ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383736-B1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2009-06-17 | — | — | EP | disclosed |
| EP-1383736-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2006-04-19 | — | — | EP | disclosed |
| US-6967220-B2 | Peptide deformylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2005-11-22 | — | — | US | disclosed |
| US-20040106795-A1 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC | 2004-06-03 | — | — | US | disclosed |
| EP-1383736-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2003002522-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2003-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106795-A1 | Peptide deformylase inhibitors | PDF, PEPD, DPEP1 | ALDH1A1 4367/4885L3MBTL1 1436/4885KMT2A 3776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.