Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423013 | 0.74 | ATM (0.44) | ATMRAB9ANPC1 | |
| SCHEMBL400031 | 0.74 | ATM (0.40) | ATMALDH1A1RAB9ANPC1 | |
| SCHEMBL5259264 | 0.69 | ATM (0.48) | MEN1KMT2AATMRAB9ANPC1 | |
| SCHEMBL14699551 | 0.66 | L3MBTL1 (0.57) | MEN1KMT2AL3MBTL1HPGDALDH1A1 | |
| SCHEMBL4620642 | 0.65 | ATM (0.48) | MEN1KMT2AATMRAB9ANPC1 | |
| SCHEMBL3535166 | 0.65 | ATM (0.48) | MEN1KMT2AATMRAB9ANPC1 | |
| SCHEMBL8424490 | 0.65 | ATM (0.48) | MEN1KMT2AATMRAB9ANPC1 | |
| SCHEMBL4559941 | 0.65 | ATM (0.48) | MEN1KMT2AATMRAB9ANPC1 | |
| SCHEMBL6081734 | 0.65 | ATM (0.44) | ATMRAB9ANPC1 | |
| SCHEMBL4288878 | 0.65 | ATM (0.44) | ATMRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1344775-B1 | Preparation of fungicidal quinazolinones and useful intermediates | DU PONT (US) | 2006-11-29 | — | — | EP | disclosed |
| EP-0922037-B1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | DU PONT (US) | 2003-10-01 | — | — | EP | disclosed |
| EP-1344775-A1 | Preparation of fungicidal quinazolinones and useful intermediates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-09-17 | — | — | EP | disclosed |
| US-6166208-A | Preparation of fungicidal quinazolinones and useful intermediates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-12-26 | — | — | US | disclosed |
| EP-0922037-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1997048684-A1 | PREPARATION OF FUNGICIDAL QUINAZOLINONES AND USEFUL INTERMEDIATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |