Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3535166 | 0.76 | ATM (0.48) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL5712412 | 0.74 | MEN1 (0.42) | ATMNPC1RAB9A | |
| SCHEMBL8424490 | 0.72 | ATM (0.48) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL5259264 | 0.72 | ATM (0.48) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL4559941 | 0.72 | ATM (0.48) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL4620642 | 0.72 | ATM (0.48) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL4288878 | 0.71 | ATM (0.44) | ATMNPC1RAB9A | |
| SCHEMBL9769252 | 0.69 | ATM (0.45) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL5250885 | 0.69 | ATM (0.45) | ATMCYP1A2CYP2A6NPC1RAB9A | |
| SCHEMBL6081734 | 0.68 | ATM (0.44) | ATMNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946095-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998026664-A1 | FUNGICIDAL QUINAZOLINONES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-06-25 | — | — | WO | disclosed |