Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | AURKA | O14965 | 2/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6873402 | 0.87 | CYP2A6 (0.42) | CYP2A6TSHRALOX15MAOAHPGD | |
| SCHEMBL5712497 | 0.82 | TSHR (0.40) | TSHRALOX15MAOAAURKAAURKB | |
| SCHEMBL5712447 | 0.79 | TSHR (0.38) | TSHRALOX15MAOAHPGDTDP1 | |
| SCHEMBL5712471 | 0.78 | MAOA (0.40) | TSHRALOX15MAOAAURKAAURKB | |
| SCHEMBL5712455 | 0.76 | AURKA (0.40) | TSHRALOX15MAOAAURKAAURKB | |
| SCHEMBL5712446 | 0.74 | MAPT (0.38) | TSHRALOX15MAOAHPGDTDP1 | |
| SCHEMBL2931225 | 0.74 | ALOX15 (0.46) | TSHRALOX15MAOAAURKAAURKB | |
| SCHEMBL5712434 | 0.73 | CSNK2A2 (0.40) | TSHRALOX15MAOAHPGDTDP1 | |
| SCHEMBL2937809 | 0.73 | ALDH1A1 (0.46) | TSHRALOX15MAOAAURKAAURKB | |
| SCHEMBL5712507 | 0.73 | ALOX15 (0.41) | TSHRALOX15MAOAAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | claimed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | claimed |
| CN-1646518-A | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | claimed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | disclosed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | KRT18, JUP, IK | CYP2A6 1364/4885TSHR 4289/4885ALOX15 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.