Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6871822 | 0.87 | CYP3A4 (0.33) | ALOX15TSHRHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL5712441 | 0.83 | ALOX15 (0.36) | ALOX15TSHRMAOAHPGDHSD17B10 | |
| SCHEMBL5712484 | 0.83 | TSHR (0.36) | ALOX15TSHRMAOAHPGDHSD17B10 | |
| SCHEMBL5712443 | 0.81 | HSD17B1 (0.47) | ALOX15TSHRHPGDHSD17B10ALDH1A1 | |
| SCHEMBL5712458 | 0.80 | ALOX15 (0.34) | ALOX15TSHRMAOAHPGDHSD17B10 | |
| SCHEMBL5712440 | 0.78 | MAPT (0.39) | ALOX15TSHRMAOAHPGDALDH1A1 | |
| SCHEMBL5712477 | 0.77 | GPR35 (0.38) | ALOX15HSD17B10SMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL5712480 | 0.74 | KCNH2 (0.44) | ALOX15TSHRMAOAHPGDHSD17B10 | |
| SCHEMBL2933993 | 0.73 | NQO1 (0.48) | ALOX15TSHRHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL2939499 | 0.73 | ALOX15 (0.44) | ALOX15TSHRMAOAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | claimed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | claimed |
| CN-1646518-A | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | claimed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| CN-100549003-C | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2009-10-14 | — | — | CN | disclosed |
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | disclosed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| CN-1646518-A | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | disclosed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | KRT18, JUP, IK | ALOX15 4723/4885TSHR 4289/4885MAOA 2890/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.