SCHEMBL5712552

SCHEMBL5712552

Clc1cnc(-c2ccccc2)nc1Cl

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.53
MEN1 O00255 3/20 0.53
HTT P42858 1/20 0.53
NPC1 O15118 4/20 0.50
RAB9A P51151 4/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
NFKB1 P19838 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
LMNA P02545 3/20 0.48
MAPT P10636 1/20 0.46
RECQL P46063 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.45
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 1/20 0.43
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
MAPK1 P28482 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28706731 0.87 KMT2A (0.42) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL30062512 0.82 RAB9A (0.43) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL17412412 0.82 KMT2A (0.52) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL10912479 0.82 L3MBTL1 (0.51) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL31515064 0.82 L3MBTL1 (0.51) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL5914190 0.80 KMT2A (0.50) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL13841426 0.80 LMNA (0.55) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL4141792 0.80 KMT2A (0.60) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL20821352 0.80 L3MBTL1 (0.54) KMT2AMEN1HTTNPC1RAB9A
SCHEMBL3810496 0.78 CYP1A2 (0.46) NPC1RAB9ASMN1; SMN2L3MBTL1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11937599-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2024-03-26 US claimed
EP-3917319-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES Monsanto Technology LLC (US) 2021-12-08 EP claimed
CN-113573584-A Microencapsulated acetamide herbicides 孟山都技术有限公司 2021-10-29 CN claimed
US-11129381-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2021-09-28 US claimed
WO-2020160223-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-08-06 WO claimed
US-20200236928-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-07-30 US claimed
US-20200163331-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2020-05-28 US claimed
EP-3638023-A1 MICROENCAPSULATED HERBICIDES Monsanto Technology LLC (US) 2020-04-22 EP claimed
WO-2018231913-A1 MICROENCAPSULATED HERBICIDES MONSANTO TECHNOLOGY LLC (US) 2018-12-20 WO claimed
WO-2000011954-A1 HERBICIDAL METHOD AVENTIS CROPSCIENCE S.A. (FR) 2000-03-09 WO claimed
WO-1992010098-A1 SAFENED HERBICIDAL SULFONAMIDE COMPOSITIONS MONSANTO COMPANY (US) 1992-06-25 WO claimed
WO-2024144215-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 솔루스첨단소재 주식회사 2024-07-04 WO disclosed
US-11937599-B2 Microencapsulated herbicides MONSANTO TECHNOLOGY LLC (US) 2024-03-26 US disclosed
WO-2024053282-A1 POLYMER, COMPOSITION, CURED PRODUCT, LAMINATE, AND ELECTRONIC COMPONENT JSR株式会社 2024-03-14 WO disclosed
WO-2023040894-A1 STABLE AGROCHEMICAL COMPOSITION COMPRISING TWO SOLID ACTIVE COMPONENTS AND ONE LIQUID ACTIVE COMPONENT AND ITS PREPARATION PROCESS ADAMA AGAN LTD. (IL) 2023-03-23 WO disclosed
WO-2002022607-A1 PYRAZOLE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2002-03-21 WO disclosed
CN-1326317-A Combinations of herbicides and safeners AVENTIS CROPSCIENCE GMBH (DE) 2001-12-12 CN disclosed
WO-2001035742-A2 HERBICIDE MEANS WITH ACYLATED AMINO PHENYL SULFONYL CARBAMIDE AVENTIS CROPSCIENCE GMBH (DE) 2001-05-25 WO disclosed
WO-2000011954-A1 HERBICIDAL METHOD AVENTIS CROPSCIENCE S.A. (FR) 2000-03-09 WO disclosed
WO-1992011761-A1 REDUCING PESTICIDAL INTERACTIONS IN CROPS MONSANTO COMPANY (US) 1992-07-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200163331-A1 MICROENCAPSULATED HERBICIDES HACL2, ACACB, HDHD5 KMT2A 1020/4885MEN1 2792/4885HTT 164/4885
US-11129381-B2 Microencapsulated herbicides HACL2, ACACB, HDHD5 KMT2A 1020/4885MEN1 2792/4885HTT 164/4885
US-11937599-B2 Microencapsulated herbicides HACL2, ACACB, HDHD5 KMT2A 1020/4885MEN1 2792/4885HTT 164/4885
US-20200236928-A1 MICROENCAPSULATED ACETAMIDE HERBICIDES HDHD5, HACL2, ACAA2 KMT2A 1044/4885MEN1 3869/4885HTT 421/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.