Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenoxyethanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.86 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.53 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.53 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 2/20 | 0.52 |
| ▸ | HTR1D | P28221 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenoxyethanol SCHEMBL15666459 | 0.95 | RECQL (0.86) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL6407076 | 0.93 | RECQL (0.83) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL7078024 | 0.93 | ALDH1A1 (0.91) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL27476573 | 0.93 | ALDH1A1 (1.00) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL9349725 | 0.93 | ALDH1A1 (1.00) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL167128 | 0.93 | ALDH1A1 (1.00) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL15708 | 0.93 | ALDH1A1 (1.00) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL9349721 | 0.92 | ALDH1A1 (0.73) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL12100847 | 0.91 | ALDH1A1 (0.79) | RECQLALDH1A1KCNA3GAANR1I2 | |
| Phenoxyethanol SCHEMBL18074838 | 0.91 | ALDH1A1 (0.95) | RECQLALDH1A1KCNA3GAANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3339382-B1 | INK, INK CARTRIDGE, AND INK JET RECORDING METHOD | CANON KK (JP) | 2020-12-09 | — | — | EP | claimed |
| EP-0551975-B1 | Disinfectant concentrate and disinfectant based on amines and alcohols and use thereof | SCHUELKE & MAYR GMBH (DE) | 1997-07-16 | — | — | EP | claimed |
| EP-0551975-A1 | Disinfectant concentrate and disinfectant based on amines and alcohols and use thereof | SCHÜLKE & MAYR GMBH (DE) | 1993-07-21 | — | — | EP | claimed |
| CN-114366695-A | Moisturizing composition and preparation method thereof | 程瑶 | 2022-04-19 | — | — | CN | disclosed |
| EP-2895587-A1 | HARD SURFACE TREATMENT COMPOSITION | Unilever N.V. (NL) | 2015-07-22 | — | — | EP | disclosed |
| US-8846981-B2 | 1,1-di[(alkylphenoxy)ethoxy]cyclohexanes | SOUTHERN LITHOPLATE, INC. (US) | 2014-09-30 | — | — | US | disclosed |
| WO-2014040869-A1 | HARD SURFACE TREATMENT COMPOSITION | UNILEVER N.V. (NL) | 2014-03-20 | — | — | WO | disclosed |
| US-8632943-B2 | Near-infrared sensitive, positive-working, image forming composition and photographic element containing a 1,1-di[(alkylphenoxy)ethoxy]cyclohexane | SOUTHERN LITHOPLATE, INC. (US) | 2014-01-21 | — | — | US | disclosed |
| US-20130197274-A1 | 1,1-DI[(ALKYLPHENOXY)ETHOXY]CYCLOHEXANES | SOUTHERN LITHOPLATE, INC. | 2013-08-01 | — | — | US | disclosed |
| US-20130196267-A1 | NEAR-INFRARED SENSITIVE, POSITIVE-WORKING, IMAGE FORMING COMPOSITION AND PHOTOGRAPHIC ELEMENT CONTAINING A 1,1-DI[(ALKYLPHENOXY)ETHOXY]CYCLOHEXANE | SOUTHERN LITHOPLATE, INC. | 2013-08-01 | — | — | US | disclosed |
| EP-1720578-A2 | BACTERIOSTATIC ESTERS FOR TOPICAL USE | Vama Farmacosmetica S.R.L. (IT) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005079852-A2 | BACTERIOSTATIC ESTERS FOR TOPICAL USE | VAMA FARMCOSMETICA S.R.L. (IT) | 2005-09-01 | — | — | WO | disclosed |
| US-20050182124-A1 | Ester bacteriostat for stabilizing cosmetics | VAMA FARMACOSMETICA S.R.L. | 2005-08-18 | — | — | US | disclosed |
| US-5897857-A | SULFHYDRYL COMPOUND SELECTED FROM CYSTEINE, HOMOCYCTEINE, GLUTATHIONE, THIOGLYCEROL, THIOMALIC ACID, 2-MERCAPTOETHANOL, MERCAPTOPROPIONIC ACIDS, DITHIOTHREITOL, THIOSALICYLIC ACID, N-ACETYL-L-CYSTEIN AND SALTS; FACIAL HAIR REMOVER | THE PROCTER & GAMBLE COMPANY (US) | 1999-04-27 | — | — | US | disclosed |
| EP-0551975-B1 | Disinfectant concentrate and disinfectant based on amines and alcohols and use thereof | SCHUELKE & MAYR GMBH (DE) | 1997-07-16 | — | — | EP | disclosed |
| US-5405606-A | Mixture of glutaraldehyde, phenoxyethanol and alcohol | EFH, INC. (US) | 1995-04-11 | — | — | US | disclosed |
| EP-0551975-A1 | Disinfectant concentrate and disinfectant based on amines and alcohols and use thereof | SCHÜLKE & MAYR GMBH (DE) | 1993-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130197274-A1 | 1,1-DI[(ALKYLPHENOXY)ETHOXY]CYCLOHEXANES | KHK, DEGS1, AKR1A1 | RECQL 2689/4885ALDH1A1 846/4885KCNA3 432/4885 |
| US-20050182124-A1 | Ester bacteriostat for stabilizing cosmetics | CUTA, PGA5, ACP3 | RECQL 3750/4885ALDH1A1 393/4885KCNA3 3710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.