SCHEMBL669540

SCHEMBL669540

O=c1oc2ccccc2c(O)c1Br

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.62
NQO1 P15559 7/20 0.61
ALDH1A1 P00352 3/20 0.61
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
ABCB11 O95342 1/20 0.61
LMNA P02545 1/20 0.61
TP53 P04637 1/20 0.61
CYP1A2 P05177 1/20 0.61
CYP3A4 P08684 1/20 0.61
CYP2C9 P11712 1/20 0.61
TSHR P16473 1/20 0.61
MAPK1 P28482 1/20 0.61
CYP2C19 P33261 1/20 0.61
PDE4D Q08499 1/20 0.61
PCSK7 Q16549 1/20 0.61
GPR35 Q9HC97 1/20 0.61
CA12 O43570 1/20 0.57
CA9 Q16790 1/20 0.57
VKORC1 Q9BQB6 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30050788 0.85 KDM4E (0.58) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL669541 0.85 KDM4E (0.58) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL7737431 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL29872 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL29379994 0.82 KDM4E (0.69) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5472418 0.82 HSD17B10 (0.54) KDM4ENQO1ALDH1A1MEN1KMT2A
Hydrochloric Acid SCHEMBL8701572 0.80 KDM4E (0.67) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5713261 0.78 KDM4E (0.65) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL23727919 0.77 KDM4E (0.62) KDM4ENQO1ALDH1A1MEN1KMT2A
SCHEMBL5459905 0.77 KDM4E (1.00) KDM4ENQO1ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665868-A2 METHODS FOR MULTIPLEXED IMAGING AND DETECTION OF TARGETS President and Fellows of Harvard College (US) 2025-12-24 EP disclosed
CN-116762002-A Sensor for unbiased proteome studies, methods of making and using the same 纳米马赛克公司 2023-09-15 CN disclosed
CN-116348613-A High throughput analysis of fixed cells 新格元生物科技有限公司 2023-06-27 CN disclosed
WO-2022220019-A1 LONG-CHAIN DNA SYNTHESIS USING NON-NATURAL BASE 国立大学法人東京工業大学 2022-10-20 WO disclosed
CN-115176027-A Compositions and methods for light-directed biomolecular barcoding 哈佛大学校长及研究员协会 2022-10-11 CN disclosed
CN-113826011-A Nano-sensor and use thereof 纳米马赛克公司 2021-12-21 CN disclosed
CN-113454238-A Compositions and methods for synthesizing nucleic acids 哈佛大学校长及研究员协会 2021-09-28 CN disclosed
WO-2021117680-A1 BIOLOGICAL SUBSTANCE IMMOBILIZATION MATERIAL 国立大学法人 東京大学 2021-06-17 WO disclosed
EP-3463485-A1 PHOTOLABILE COMPOSITIONS AS A STABILIZATION PLATFORM Nanoly Bioscience, Inc. (US) 2019-04-10 EP disclosed
US-20190091346-A1 PHOTOLABILE COMPOSITIONS AS A STABILIZATION PLATFORM NANOLY BIOSCIENCE, INC. (US) 2019-03-28 US disclosed
US-8343710-B1 Photodegradable groups for tunable polymeric materials THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) 2013-01-01 US disclosed
WO-2012024558-A2 LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2012-02-23 WO disclosed
US-20110178281-A1 Photocleavable Linker Methods and Compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2011-07-21 US disclosed
US-7923562-B2 Photocleavable linker methods and compositions THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2011-04-12 US disclosed
US-20100022761-A1 PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY 2010-01-28 US disclosed
JP-2007319064-A METHOD FOR EXPRESSING PROTEIN SITE-SPECIFICALLY INTRODUCED MODIFIED AMINO ACID JAPAN SCIENCE & TECHNOLOGY AGENCY 2007-12-13 JP disclosed
EP-0091141-B1 PROCESS FOR THE PREPARATION OF THIOETHERS GIST-BROCADES N.V. (NL) 1985-07-31 EP disclosed
US-4496720-A REACTING SILATED THIO WITH ORGANIC HALIDE, SULATE OR SULFONATE IN PRESENCE OF HEXAMETHYLPHOSPHORIC TRIAMIDE GIST-BROCADES N.V. (NL) 1985-01-29 US disclosed
EP-0091141-A1 Process for the preparation of thioethers GIST-BROCADES N.V. (NL) 1983-10-12 EP disclosed
EP-0088831-A1 Process for the preparation of thioethers GIST-BROCADES N.V. (NL) 1983-09-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190091346-A1 PHOTOLABILE COMPOSITIONS AS A STABILIZATION PLATFORM TTPA, CRYAB, CRYAA KDM4E 2845/4885NQO1 1345/4885ALDH1A1 2502/4885
US-20110178281-A1 Photocleavable Linker Methods and Compositions NSUN2, RNGTT, METTL16 KDM4E 254/4885NQO1 412/4885ALDH1A1 1111/4885
US-20100022761-A1 PHOTOCLEAVABLE LINKER METHODS AND COMPOSITIONS NSUN2, RNGTT, METTL16 KDM4E 254/4885NQO1 412/4885ALDH1A1 1111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.