Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6101710 | 0.94 | TRPV1 (0.50) | TRPV1TRPA1HIF1AEPAS1FAAH | |
| SCHEMBL5714459 | 0.91 | LIPE (0.45) | TRPV1TRPA1KDM4EALDH1A1ALOX15 | |
| SCHEMBL6102857 | 0.89 | HIF1A (0.59) | TRPV1TRPA1KDM4EALDH1A1HIF1A | |
| SCHEMBL5715284 | 0.87 | LIPE (0.61) | FAAHLIPE | |
| SCHEMBL5714276 | 0.86 | LIPE (0.46) | TRPV1TRPA1HIF1AEPAS1FAAH | |
| SCHEMBL5714790 | 0.84 | FAAH (0.43) | TRPV1TRPA1KDM4EALDH1A1ALOX15 | |
| SCHEMBL6102111 | 0.83 | TRPV1 (0.51) | TRPV1TRPA1SIGMAR1ADORA3HTR2A | |
| SCHEMBL5714468 | 0.83 | KDM4E (0.49) | KDM4EALDH1A1ALOX15SIGMAR1FAAH | |
| SCHEMBL5714955 | 0.82 | HTR2A (0.55) | KDM4EALDH1A1ALOX15SIGMAR1FAAH | |
| SCHEMBL5715475 | 0.82 | SIGMAR1 (0.46) | KDM4EALDH1A1ALOX15SIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060160820-A1 | Substituted piperazine carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | claimed |
| US-20060160820-A1 | Substituted piperazine carbamates | NOVO NORDISK A/S (DK) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060160820-A1 | Substituted piperazine carbamates | LIPE, PNLIP, LPL | TRPV1 1597/4885TRPA1 2010/4885KDM4E 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.