SCHEMBL5715633

SCHEMBL5715633

CCCCP(CC)c1ccc(F)cc1F

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.32
ALDH1A1 P00352 1/20 0.31
HDAC3 O15379 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
GCGR P47871 1/20 0.31
FAAH O00519 1/20 0.31
NFE2L2 Q16236 3/20 0.30
ICMT O60725 2/20 0.30
GHSR Q92847 1/20 0.30
IDO1 P14902 1/20 0.30
AGXT P21549 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5715999 0.93 ICMT (0.34) HTR7GCGRICMTGHSR
SCHEMBL6792568 0.90 CES2 (0.32) HTR7ALDH1A1GCGRFAAHNFE2L2
SCHEMBL6786630 0.88 GHSR (0.35) HTR7GCGRICMTGHSR
SCHEMBL5716153 0.88 GHSR (0.35) HTR7GCGRICMTGHSR
SCHEMBL2544485 0.88 GCGR (0.34) HTR7ALDH1A1GCGRFAAHICMT
SCHEMBL6786145 0.83 ICMT (0.34) HTR7GCGRICMTGHSR
SCHEMBL6793753 0.83 ICMT (0.34) HTR7GCGRICMTGHSR
SCHEMBL5715807 0.82 CES2 (0.36) ALDH1A1NFE2L2IDO1AGXT
SCHEMBL5716125 0.79 LMNA (0.35) ALDH1A1
SCHEMBL5716099 0.79 HDAC3 (0.37) ALDH1A1HDAC3HDAC1HDAC2NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed