Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.47 |
| ▸ | SHBG | P04278 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 5/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | PGR | P06401 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 2/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148415 | 0.82 | SHBG (0.69) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL10867342 | 0.82 | SHBG (0.69) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL10867348 | 0.82 | SHBG (0.69) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL28750427 | 0.78 | LMNA (0.66) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL11500511 | 0.77 | LMNA (0.65) | LMNASHBGNR3C1MAPTMEN1 | |
| SCHEMBL25433090 | 0.74 | SMN1; SMN2 (0.67) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL28021790 | 0.74 | SMN1; SMN2 (0.66) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL10723863 | 0.73 | SMN1; SMN2 (0.62) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL28716683 | 0.73 | SMN1; SMN2 (0.65) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 | |
| SCHEMBL3777671 | 0.72 | LMNA (0.67) | LMNASHBGSMN1; SMN2SERPINA6NR3C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598150-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | The Hospital For Sick Children (CA) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018643-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2012-02-09 | — | — | WO | disclosed |