Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11852002 | 0.82 | NR3C1 (0.60) | LMNACYP3A4HSD17B10NR3C1PGR | |
| SCHEMBL11852007 | 0.82 | NR3C1 (0.60) | LMNACYP3A4HSD17B10NR3C1PGR | |
| SCHEMBL10865415 | 0.82 | LMNA (0.74) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| SCHEMBL13558385 | 0.82 | LMNA (0.74) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| SCHEMBL12738227 | 0.81 | LMNA (0.72) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| SCHEMBL11208456 | 0.81 | LMNA (0.72) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| SCHEMBL10867348 | 0.80 | SHBG (0.69) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| SCHEMBL148415 | 0.80 | SHBG (0.69) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| SCHEMBL10867342 | 0.80 | SHBG (0.69) | LMNAMAPTCYP19A1CYP3A4HSD17B10 | |
| Methandrostenolone SCHEMBL4435272 | 0.79 | LMNA (1.00) | LMNAMAPTCYP19A1CYP3A4HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4185101-A | ANTIMITOTIC | SCHERING CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |