SCHEMBL5716009

SCHEMBL5716009

CCCCC(CC)CCN(c1cccc(F)c1F)C(F)(F)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NR1H2 P55055 1/20 0.31
NR1H3 Q13133 1/20 0.31
CA2 P00918 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5716436 0.85 NR1H2 (0.38) NR1H2NR1H3
SCHEMBL6791085 0.83 NR1H2 (0.34) ALDH1A1NR1H2NR1H3
SCHEMBL6790671 0.81 LMNA (0.33)
SCHEMBL5716173 0.79 ALDH1A1 (0.35) ALDH1A1KDM4ECA2CYP3A4
SCHEMBL5716224 0.79
SCHEMBL6792064 0.78
SCHEMBL5716246 0.78 ALDH1A1 (0.35) ALDH1A1KDM4ECA2CYP3A4
SCHEMBL6797889 0.75
SCHEMBL5716050 0.74 ALDH1A1 (0.32) ALDH1A1KDM4ECA2CYP3A4
SCHEMBL7612249 0.72 ESR1 (0.38) ALDH1A1NR1H2NR1H3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed