SCHEMBL5716111

SCHEMBL5716111

CCCCCCCCCP(c1ccccc1)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
EPHX2 P34913 1/20 0.33
PKM P14618 1/20 0.33
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
HTT P42858 2/20 0.32
KCNH2 Q12809 1/20 0.32
NAAA Q02083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6800934 0.86 KCNN4 (0.35) SMN1; SMN2HTT
SCHEMBL5715692 0.83 GAA (0.31)
SCHEMBL7609757 0.80 RORA (0.32) MEN1KMT2ASMN1; SMN2KCNH2
SCHEMBL5716304 0.74 ICMT (0.34) MEN1KMT2ASMN1; SMN2EPHX2KCNH2
SCHEMBL49664 0.72 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL15659895 0.72 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6288234 0.72 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL6792024 0.72 CYP3A4 (0.35)
SCHEMBL6288656 0.72 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1
SCHEMBL4416335 0.72 DNM1 (0.40) DNM1MEN1KMT2ATP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed
EP-1252166-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2002-10-30 EP disclosed
WO-2001042249-A1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 COMPOUNDS AND PROCESSES USING THEM EXXON CHEMICAL PATENTS INC. (US) 2001-06-14 WO disclosed