Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL5715995 | 0.95 | SIGMAR1 (0.40) | KDM4EALDH1A1NPC1RAB9ASIGMAR1 | |
| Biphenyl SCHEMBL5715585 | 0.92 | NPC1 (0.38) | KDM4EALDH1A1NPC1RAB9ASIGMAR1 | |
| Biphenyl SCHEMBL5716483 | 0.88 | ALDH1A1 (0.41) | KDM4EALDH1A1NPC1RAB9ASIGMAR1 | |
| Biphenyl SCHEMBL5716100 | 0.84 | NPC1 (0.37) | KDM4EALDH1A1NPC1RAB9ASIGMAR1 | |
| Biphenyl SCHEMBL5716461 | 0.82 | SIGMAR1 (0.46) | ALDH1A1NPC1RAB9ASIGMAR1DRD2 | |
| SCHEMBL6466610 | 0.81 | ALDH1A1 (0.39) | KDM4EALDH1A1HDAC3HDAC1HDAC2 | |
| Biphenyl SCHEMBL5716464 | 0.78 | ALDH1A1 (0.49) | KDM4EALDH1A1NPC1RAB9AHDAC3 | |
| SCHEMBL5716579 | 0.74 | ALDH1A1 (0.33) | ALDH1A1CYP3A4TSHR | |
| Biphenyl SCHEMBL5715691 | 0.74 | NPC1 (0.36) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| Biphenyl SCHEMBL7742046 | 0.73 | SIGMAR1 (0.59) | KDM4EALDH1A1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661900-A1 | Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them | ExxonMobil Chemical Patents Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |