Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL5716483 | 0.90 | ALDH1A1 (0.41) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| Biphenyl SCHEMBL5715585 | 0.87 | NPC1 (0.38) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| Biphenyl SCHEMBL5716397 | 0.84 | KDM4E (0.41) | NPC1RAB9AALDH1A1KDM4ECYP1A2 | |
| Biphenyl SCHEMBL5715995 | 0.82 | SIGMAR1 (0.40) | NPC1RAB9AALDH1A1KDM4ESIGMAR1 | |
| SCHEMBL6466610 | 0.75 | ALDH1A1 (0.39) | ALDH1A1KDM4EMAPT | |
| Biphenyl SCHEMBL5715691 | 0.75 | NPC1 (0.36) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| Biphenyl SCHEMBL5715728 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHTTSIGMAR1 | |
| Biphenyl SCHEMBL5716337 | 0.72 | NPC1 (0.35) | NPC1RAB9ASIGMAR1 | |
| SCHEMBL7647461 | 0.72 | — | — | |
| SCHEMBL5715894 | 0.70 | GRIA4 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1661900-A1 | Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them | ExxonMobil Chemical Patents Inc. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |