Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 8/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716091 | 0.88 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL5715608 | 0.83 | ALDH1A1 (0.37) | ALDH1A1KDM4EGRIA4MEN1MAPT | |
| Biphenyl SCHEMBL5716397 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EMMP2CYP3A4TSHR | |
| Biphenyl SCHEMBL5715995 | 0.79 | SIGMAR1 (0.40) | ALDH1A1KDM4EMMP2SOAT1 | |
| Biphenyl SCHEMBL5715585 | 0.78 | NPC1 (0.38) | ALDH1A1KDM4EMAPTADRB2 | |
| SCHEMBL5715966 | 0.78 | ALDH1A1 (0.40) | ALDH1A1KDM4ECYP3A4TSHR | |
| Biphenyl SCHEMBL5716483 | 0.76 | ALDH1A1 (0.41) | ALDH1A1KDM4EGRIA4MAPTCYP3A4 | |
| SCHEMBL5715894 | 0.75 | GRIA4 (0.32) | GRIA4AMY1AGCGRTRPV3 | |
| Biphenyl SCHEMBL5716100 | 0.75 | NPC1 (0.37) | ALDH1A1KDM4EMAPT | |
| SCHEMBL5716406 | 0.72 | ALDH1A1 (0.42) | ALDH1A1KDM4ECYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1252166-B1 | OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM | EXXONMOBIL CHEM PATENTS INC (US) | 2005-11-09 | — | — | EP | disclosed |