Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.42 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5500095 | 0.88 | NPC1 (0.47) | NPC1RAB9AP2RX7TSHRHTT | |
| SCHEMBL5716638 | 0.87 | NPC1 (0.49) | NPC1RAB9AP2RX7TSHRHTT | |
| SCHEMBL5690435 | 0.85 | NPC1 (0.65) | NPC1RAB9AP2RX7TSHRHTT | |
| SCHEMBL5716639 | 0.84 | RAB9A (0.39) | NPC1RAB9ATSHRHTTHSD17B10 | |
| SCHEMBL5716644 | 0.84 | NPC1 (0.39) | NPC1RAB9AP2RX7TSHRHTT | |
| SCHEMBL5177997 | 0.84 | NPC1 (0.39) | NPC1RAB9AP2RX7TSHRHTT | |
| SCHEMBL5177699 | 0.80 | KDM4E (0.59) | NPC1RAB9AHTTMEN1ALDH1A1 | |
| SCHEMBL5716646 | 0.78 | KCNA3 (0.40) | NPC1RAB9AHPGDMEN1ALDH1A1 | |
| SCHEMBL551662 | 0.77 | TAS1R3 (0.45) | NPC1RAB9AGPR139PBRM1HPGD | |
| SCHEMBL3477262 | 0.77 | PBRM1 (0.53) | TSHRPBRM1HPGDMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1727804-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-06 | — | — | EP | disclosed |
| WO-2005095351-A1 | N1 - ((PYRAZOL-1-YMETHYL) -2-METHYLPHENYL)- PHATALAMIDE DERIVATIVES AND RELATED COMPOUNDS INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2005-10-13 | — | — | WO | disclosed |