Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717227 | 0.89 | ALDH1A1 (0.64) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717100 | 0.89 | ALDH1A1 (0.64) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717102 | 0.89 | ALDH1A1 (0.64) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717121 | 0.87 | ALDH1A1 (0.56) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717089 | 0.84 | ALDH1A1 (0.58) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717002 | 0.81 | HCRTR1 (0.62) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717267 | 0.81 | ALDH1A1 (0.55) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 | |
| SCHEMBL5717208 | 0.79 | RAB9A (0.70) | ALDH1A1KDM4ESMN1; SMN2KMT2ALMNA | |
| SCHEMBL5717188 | 0.79 | FKBP1A (0.63) | FKBP1AALDH1A1KDM4EKMT2ALMNA | |
| SCHEMBL20291418 | 0.78 | BRD4 (0.68) | FKBP1AALDH1A1KDM4ESMN1; SMN2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1664010-A1 | SULFONAMIDES ANTAGONISING N-TYPE CALCIUM CHANNELS | Vernalis (R&D) Limited (GB) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005068448-A1 | SULFONAMIDES ANTAGONISING N-TYPE CALCIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2005-07-28 | — | — | WO | disclosed |