Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL429933 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL21004874 | 0.81 | L3MBTL1 (0.47) | ALDH1A1MAPK1HPGDRAB9ASMN1; SMN2 | |
| SCHEMBL31232589 | 0.80 | ALDH1A1 (0.43) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL201614 | 0.78 | L3MBTL1 (0.50) | ALDH1A1MAPK1HTTHSD17B10HPGD | |
| SCHEMBL29356458 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL25644774 | 0.76 | ALDH1A1 (0.54) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL1627501 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL200742 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MAPK1HTTHSD17B10HPGD | |
| SCHEMBL24723508 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MAPK1HSD17B10HPGDBCL2L1 | |
| SCHEMBL30223212 | 0.76 | CYP1A2 (0.58) | ALDH1A1MAPK1HTTCYP2A6RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115703694-A | Alkyl substituted fluorene and derivative and preparation method thereof | 陕西维世诺新材料有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-1922156-A | Substituted triazoles as sodium channel blockers | MERCK & CO INC (US) | 2007-02-28 | — | — | CN | disclosed |
| EP-1689743-A2 | PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS | Pharmacia Corporation (US) | 2006-08-16 | — | — | EP | disclosed |
| WO-2005042521-A2 | PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2005-05-12 | — | — | WO | disclosed |
| EP-1501827-A2 | PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACID AND THEIR USE AS PROTEASE INHIBITORS | Pharmacia Corporation (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091247-A2 | PIPERIDINYL-AND PIPERAZINYL-SULFONYLMETHYL HYDROXAMIC ACIDS AND THEIR USE AS PROTEASE INHIBITORS | PHARMACIA CORPORATION (US) | 2003-11-06 | — | — | WO | disclosed |