SCHEMBL24723508

SCHEMBL24723508

Fc1cc(-c2ccccc2-c2ccccc2)cc(F)c1Br

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.48
MAPK1 P28482 2/20 0.48
RPS6KA3 P51812 1/20 0.46
FEN1 P39748 3/20 0.44
ALOX5AP P20292 2/20 0.44
ESR1 P03372 1/20 0.40
BACE1 P56817 1/20 0.39
ALOX5 P09917 1/20 0.39
PTGS1 P23219 3/20 0.39
MEN1 O00255 2/20 0.39
PTGS2 P35354 2/20 0.39
KMT2A Q03164 2/20 0.39
HPGD P15428 2/20 0.39
FABP2 P12104 1/20 0.39
TSHR P16473 1/20 0.39
AKR1C4 P17516 1/20 0.39
ADRA2B P18089 1/20 0.39
CHRM3 P20309 1/20 0.39
HTR2C P28335 1/20 0.39
DRD3 P35462 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24026071 0.84 PTPRC (0.50) ALDH1A1FEN1ALOX5APBACE1MAPT
SCHEMBL23989236 0.84 ALDH1A1 (0.52) ALDH1A1MAPK1FEN1ALOX5APESR1
SCHEMBL1536568 0.81 ALDH1A1 (0.44) ALDH1A1MAPK1RPS6KA3ESR1BACE1
SCHEMBL24723198 0.80 RPS6KA3 (0.47) ALDH1A1MAPK1RPS6KA3FEN1ALOX5AP
SCHEMBL4354107 0.77 ACMSD (0.47) ALDH1A1KMT2AAKR1C3AKR1C2AKR1C1
SCHEMBL31232665 0.77 MAPK1 (0.41) ALDH1A1MAPK1RPS6KA3FEN1ALOX5AP
SCHEMBL5717385 0.76 ALDH1A1 (0.50) ALDH1A1MAPK1BACE1MEN1KMT2A
SCHEMBL19400433 0.75 MEN1 (0.50) FEN1ALOX5APESR1BACE1ALOX5
SCHEMBL30378050 0.75 BACE1 (0.44) ALDH1A1MAPK1RPS6KA3BACE1ALOX5
SCHEMBL26422275 0.75 BACE1 (0.44) ALDH1A1MAPK1RPS6KA3BACE1ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022260119-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE 出光興産株式会社 2022-12-15 WO disclosed