SCHEMBL29356458

SCHEMBL29356458

Brc1cccc(-c2ccccc2)c1Br

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.68
MAPK1 P28482 3/20 0.68
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
CYP2A6 P11509 1/20 0.42
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
NFKB1 P19838 1/20 0.41
RAB9A P51151 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
NR1H2 P55055 1/20 0.40
NR1H3 Q13133 1/20 0.40
BACE1 P56817 1/20 0.39
DPP4 P27487 1/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1627501 1.00 ALDH1A1 (0.68) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
Water SCHEMBL2804005 0.98 ALDH1A1 (0.65) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
SCHEMBL27830861 0.98 ALDH1A1 (0.65) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
Bromide SCHEMBL6343986 0.95 ALDH1A1 (0.62) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
Bicarbonate SCHEMBL11404243 0.91 ALDH1A1 (0.58) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
SCHEMBL7519292 0.91 ALDH1A1 (0.62) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
Acetic Acid SCHEMBL28274416 0.88 ALDH1A1 (0.54) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
SCHEMBL429933 0.87 ALDH1A1 (0.62) ALDH1A1MAPK1HSD17B10HPGDBCL2L1
SCHEMBL30292627 0.87 ALDH1A1 (0.52) ALDH1A1MAPK1TP53MAPTNFKB1
SCHEMBL10664063 0.84 CYP2A6 (0.50) ALDH1A1MAPK1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122059997-A Palladium complex modified by norbornane skeleton monophosphine ligand, and preparation method and application thereof 滨州魏桥国科高等技术研究院 2026-05-19 CN disclosed
CN-119638984-A Polyaramid hole transport material, synthesis method thereof and perovskite solar cell 浙江大学 2025-03-18 CN disclosed
CN-111683942-B Compound, organic light-emitting device and display device SK 株式会社 2024-10-25 CN disclosed
CN-112409239-B Organic electroluminescent device and polycyclic compound for organic electroluminescent device 三星显示有限公司 2024-08-27 CN disclosed
CN-114591318-B Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2024-06-21 CN disclosed
CN-116987299-A Film, preparation method thereof, photoelectric device and display device 广东聚华印刷显示技术有限公司 2023-11-03 CN disclosed
CN-116283938-A Light-emitting element and amine compound for light-emitting element 三星显示有限公司 2023-06-23 CN disclosed
CN-115521336-A Organic phosphorus compound containing nitrogen heterocycle, preparation method thereof and light-emitting device 广东聚华印刷显示技术有限公司 2022-12-27 CN disclosed
CN-109843850-B Fluorene-based compound, organic light emitting device using the same, and method of manufacturing the same 株式会社LG化学 2022-12-16 CN disclosed
US-11444252-B2 Nitrogen-containing compound, organic electroluminescent device and electronic apparatus SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-09-13 US disclosed
CN-114957269-A Nitrogen-containing compound and light-emitting device including same 三星显示有限公司 2022-08-30 CN disclosed
US-20220216426-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-07 US disclosed
CN-114634519-A Light emitting device and polycyclic compound for light emitting device 三星显示有限公司 2022-06-17 CN disclosed
CN-114591318-A Pyrazolo heterocyclic compound, preparation method thereof, pharmaceutical composition and application 中国医学科学院药物研究所 2022-06-07 CN disclosed
CN-114514232-A Organic electroluminescent element and electronic device 出光兴产株式会社 2022-05-17 CN disclosed
CN-114450815-A Organic electroluminescent element and electronic device 出光兴产株式会社 2022-05-06 CN disclosed
US-11233200-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-01-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11233200-B2 Condensed cyclic compound, composition including the same, and organic light-emitting device including the condensed cyclic compound CRY1, CRY2, MCM4 ALDH1A1 1675/4885MAPK1 1782/4885HSD17B10 3165/4885
US-20220216426-A1 NITROGEN-CONTAINING COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS NCL, DNMT3A, NUDT1 ALDH1A1 1167/4885MAPK1 3390/4885HSD17B10 3233/4885
US-11444252-B2 Nitrogen-containing compound, organic electroluminescent device and electronic apparatus NCL, DNMT3A, NUDT1 ALDH1A1 1167/4885MAPK1 3390/4885HSD17B10 3233/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.