Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 1/20 | 0.54 |
| ▸ | PDE1A | P54750 | 1/20 | 0.54 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.54 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.54 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | GCK | P35557 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717595 | 0.90 | KMT2A (0.55) | KMT2AMEN1PKMSMN1; SMN2POLB | |
| SCHEMBL5717756 | 0.84 | ALDH1A1 (0.58) | KMT2AMEN1SMN1; SMN2POLBPDE5A | |
| SCHEMBL5867802 | 0.78 | CDK2 (0.51) | SMN1; SMN2POLBTDP1PDE5APDE1A | |
| SCHEMBL13401399 | 0.77 | KMT2A (0.56) | KMT2AMEN1PKMSMN1; SMN2POLB | |
| SCHEMBL1514790 | 0.77 | KMT2A (0.64) | KMT2AMEN1PKMSMN1; SMN2POLB | |
| SCHEMBL5717639 | 0.75 | ALDH1A1 (0.56) | KMT2AMEN1SMN1; SMN2POLBPDE5A | |
| SCHEMBL3431552 | 0.75 | KMT2A (0.91) | KMT2AMEN1PKMSMN1; SMN2POLB | |
| SCHEMBL8351289 | 0.72 | THRB (0.63) | KMT2AMEN1SMN1; SMN2POLBKDM4E | |
| SCHEMBL27599948 | 0.72 | KDM4E (0.78) | SMN1; SMN2PDE5APDE1APDE1BPDE1C | |
| SCHEMBL8350301 | 0.72 | ALDH1A1 (0.54) | KMT2AMEN1POLBPDE5APDE1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |