Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | PDE5A | O76074 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | FZD7 | O75084 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717756 | 0.90 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL5717595 | 0.84 | KMT2A (0.55) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL5717620 | 0.78 | KDM4E (0.74) | SMN1; SMN2RAB9ACSNK2A1PDE5AKDM4E | |
| SCHEMBL5717707 | 0.77 | TSHR (0.71) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL3253804 | 0.76 | ROCK1 (0.68) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL29530751 | 0.76 | CSNK2A1 (0.50) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL5717607 | 0.75 | KMT2A (0.56) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL3653730 | 0.74 | ROCK2 (0.60) | ALDH1A1CSNK2A1LMNAPDE5AKDM4E | |
| SCHEMBL16434543 | 0.73 | LMNA (0.59) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A | |
| SCHEMBL1514790 | 0.73 | KMT2A (0.64) | ALDH1A1SMN1; SMN2POLBRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |
| US-20060211636-A1 | Macrolide Antibiotics | ALIHODZIC SULEJMAN | 2006-09-21 | — | — | US | disclosed |
| US-20050215495-A1 | Macrolide antibiotics | ALIHODZIC SULEJMAN | 2005-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215495-A1 | Macrolide antibiotics | IL1R1, MRPL12, RPS21 | ALDH1A1 2549/4885SMN1; SMN2 3554/4885POLB 2625/4885 |
| US-20060211636-A1 | Macrolide Antibiotics | IL1R1, MRPL12, RPS21 | ALDH1A1 2549/4885SMN1; SMN2 3554/4885POLB 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.