Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CD69 | Q07108 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5717682 | 0.86 | ALDH1A1 (0.42) | HSD17B10KMT2APKMHTT | |
| SCHEMBL92985 | 0.75 | THRA (0.42) | KMT2ATHRBKDM4ETHRA | |
| SCHEMBL82592 | 0.75 | THRB (0.43) | KMT2APTPN1THRBKDM4EHTT | |
| SCHEMBL2059331 | 0.73 | KMT2A (0.46) | ALOX15TSHRHSD17B10CD69KMT2A | |
| SCHEMBL23147036 | 0.70 | KDM4E (0.44) | KMT2APKMKDM4EHTT | |
| SCHEMBL6746937 | 0.70 | THRB (0.54) | ALOX15TSHRHSD17B10KMT2ATHRB | |
| SCHEMBL5717583 | 0.70 | KMT2A (0.43) | ALOX15CD69KMT2APTPN1THRB | |
| SCHEMBL15322103 | 0.68 | KDM4E (0.42) | TSHRHSD17B10KMT2AKDM4EHTT | |
| SCHEMBL13603834 | 0.68 | KMT2A (0.44) | ALOX15HSD17B10CD69KMT2APKM | |
| SCHEMBL2058988 | 0.68 | KMT2A (0.44) | ALOX15CD69KMT2APKMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1363925-B1 | MACROLIDE ANTIBIOTICS | GLAXO GROUP LTD (GB) | 2006-11-15 | — | — | EP | disclosed |